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Mesothelioma - What Causes Mesothelioma?Like all cancers, the symptoms of mesothelioma can be similar to other diseases. However the early diagnosis and treatment can help improve the chances of survival for patients.Asbestos is the main cause of mesothelioma. Asbestos is a group of minerals which can be split into thin, long fibres. When inhaled or ingested asbestos fibers can become stuck in the lining of certain organs.Exposure to AsbestosThe? most proven mesothelioma-related cause is exposure to asbestos. Asbestos is a mineral that occurs naturally is composed of tough and microscopic fibers. It was widely used in buildings, vehicles, and dozens other construction materials between the 1930s and the beginning of the 1980s because it was impervious to water, fire and sound. The makers of asbestos-based products were aware about its health risks but didn't inform the public about it.Those who worked directly with asbestos or handled products made from it were at greatest danger of exposure. Mining, asbestos removal, shipbuilding and other industrial jobs exposed workers to huge amounts of asbestos. The workers also had to be exposed to asbestos-containing products, including shingles, pipes, glues and talcum powder. In the United States, chrysotile asbestos is the most frequently employed. Other asbestos types like amosite or crocidolite have also been linked to mesothelioma.Mesothelioma symptoms usually do not manifest until years after exposure to asbestos. Once they do, the condition can progress rapidly and cause death. The lungs are the ones most frequently affected (pleural mesothelioma) However, it can also affect the lining of your stomach, heart, or testicles.Asbestos fibres that are inhaled or ingested adhere to the cells that line the internal organs and tissues. Over time, this causes genetic mutations that can lead to cancer. The cells that are affected multiply uncontrollably, forming tumors.Workers in industries with a high exposure to asbestos have higher risk of developing mesothelioma compared to those who don't. Those at greatest risk are those who held blue-collar jobs or served in the military. However, mesothelioma may develop in women who were exposed to asbestos, in particular in the case of family members exposed to asbestos while at work.Secondary exposure can occur when a person who is at risk for mesothelioma brings asbestos fibers home on their clothing and other clothing. This has happened to spouses of asbestos-exposed people, as well as some hairdressers and tile workers. Some studies have found that a mineral similar to asbestos known as erionite can increase the risk of mesothelioma, however, this hasn't been proven elsewhere.Exposure to mineralsMesothelioma results from the transformation of cells that line particular parts of the body, such as the chest's lining (pleura) and abdominal cavities. Mesothelioma may also develop in the linings of the heart (pericardium), or testicles. The disease is typically caused by exposure to asbestos, but there are other causes.Asbestos is a naturally occurring mineral composed of strong and microscopic fibers. It was used for building material, in brakes for automobiles, and for a variety other products in the 1930s and 1980s due to its resistant to water, fire, and sound. Many workers in the military or construction were exposed to asbestos. Workers who handled and removed asbestos were particularly at risk of breathing asbestos-containing particles.Although the exact mesothelioma risk is dependent on the job, any type of asbestos exposure can increase a person's likelihood of developing the disease. Mesothelioma is linked to various jobs, but it more commonly affects miners, millers, and shipyard workers, as well as asbestos producers. It has been observed in those who work in the manufacturing line of aircraft and automobiles, as well as those that sand or handle insulation.Mesothelioma typically develops slowly, however symptoms can occur between 20 and 60 years after exposure to asbestos. It is essential for everyone to talk to a physician about mesothelioma even if they've not worked with asbestos before. The earlier cancer is detected, the easier it is to treat successfully.In the past, mesothelioma wasn't diagnosed until it had progressed. Mesothelioma is a rare kind of cancer, which is why doctors often overlook the signs like persistent coughing or breathing difficulties.Asbestos was eliminated by the 1980s. However, those who worked in the military or in the industrial sector before this time are still at higher risk of mesothelioma. Researchers have recently discovered other kinds of exposure to mineral which increase the risk of mesothelioma. For instance, a mineral known as erionite is found in the soil of certain regions of Turkey and is used to create materials in the area. Studies of the local population that is exposed to a lot of erionite have discovered that men in these communities are more likely to develop mesothelioma more than women. In Italy, the same thing has been observed with respect to a different mineral called fluoroedenite.GeneticsThe? mesothelium is afflicted by this type of cancer. It is most prevalent in the lining of the chest cavity (pleura), but it can also affect the tissue around the abdomen, heart and testicles.Doctors have linked mesothelioma with the mutation in the gene known as BAP1. This gene regulates a process that creates calcium in cells, and when it is altered it makes a person more likely to develop cancerous cells. Researchers have discovered that BAP1 mutations are present in 70 percent of patients with mesothelioma. This discovery has made mesothelioma easier to detect and has increased screening, particularly for people with a family history.In addition to BAP1 Researchers have also identified numerous other genetic mutations that could lead to mesothelioma. These mutations also helped mesothelioma experts better understand the disease and manage it.Although genetics may be a factor in mesothelioma, asbestos is still the leading risk factor for the cancer. Some asbestos-exposure sufferers do not develop cancer, but others with no genetic predisposition could develop mesothelioma over a long time. Paraoccupational or secondary asbestos exposure can occur when coworkers who have been exposed to asbestos carry fibers home on their skin and clothing.In some cases mesothelioma can be found in families due to a combination of genetics as well as asbestos exposure. Most mesothelioma appears to be an unrelated disease and doesn't appear to have any family history.Asbestos-related mesothelioma could be a serious condition. But research continues to make significant progress in the treatment of patients as well as their recovery options. Asbestos is banned in a number of countries, and researchers are striving to improve treatment for mesothelioma with more effective drugs, more targeted surgeries and a more effective diagnostic test. Download a free copy our Mesothelioma Guide to learn about how these recent advancements could help you. This comprehensive guide contains the complete list of mesothelioma treatment options that include the most up-to-date clinical trials and promising alternative treatments. The guide is available to download by filling out our short, online form or calling us directly.<img width="318" src=" |
